Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary Targeto-linked glycosylation

General description

Used as an inhibitor of O-linked glycosylation in a variety of cell lines. It has also been used to inhibit 2,3(O)-sialyltransferase and disrupt glycoprotein targeting in HT-29 cells. Substrate for N-acetyl-β-D-glucosaminyltransferase.

Used as an inhibitor of O-linked glycosylation in a variety of cell lines. Also inhibits 2,3(O)-sialyltransferase and disrupts glycoprotein targeting in HT-29 cells. Substrate for N-acetyl-β-D-glucosaminyltransferase.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Huet, G., et al. 1998. J. Cell Biol. 141, 1311.Kuan, S.-F., et al. 1989. J. Biol. Chem. 264, 19271.

Packaging

100 mg in Plastic ampoule

Warning

Toxicity: Standard Handling (A)